NAD+ and Skin health
Have you ever noticed younger people tend to develop less brown spots after the summer?
Hopefully the following will help you better understand why.
- UV radiation damages skin cell DNA and generates oxidative stress
- In response, the enzyme PARP1 is activated to initiate DNA repair, a process that consumes large amounts of NAD+.
- This process brings down NAD+ levels significantly. In addition to this as we age our baseline NAD+ levels go down significantly.
- This added depletion from age in addition to the UV radiation may cause a longer period of time for the DNA to be repaired, thereby increasing the probability of cell signaling for increased melanin production which causes brown spots.
- Using NAD+ boosters such as NMN and NRC help increase baseline NAD levels, especially when efficaciously dosed. Based on studies these seem to be the 2 ideal supplements to take.
We here at Lab Tested Supplements sell both NMN and NRC, efficaciously dosed at 1gram per day, no fillers, and 3rd party COA's with every lot# of every supplement we sell. Look at our heavy metal results and see if you can find another brand with lower levels. We sell high quality supplements manufactured under stringent standards.
I would like to see more human studies in this area. Here are some interesting studies to look at though
A few interesting studies
A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention
Oral nicotinamide reduces transepidermal water loss: a randomized controlled trial
β-Nicotinamide Mononucleotide Enhances Skin Barrier Function and Attenuates UV-B-Induced Photoaging in Mice